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Motoshi Suzuki Selected Research

Receptor Tyrosine Kinase-like Orphan Receptors

3/2021Inhibition of heat shock protein 90 destabilizes receptor tyrosine kinase ROR1 in lung adenocarcinoma.
1/2019ROR1-CAVIN3 interaction required for caveolae-dependent endocytosis and pro-survival signaling in lung adenocarcinoma.
2/2016Receptor tyrosine kinase-like orphan receptor 1, a target of NKX2-1/TTF-1 lineage-survival oncogene, inhibits apoptosis signal-regulating kinase 1-mediated pro-apoptotic signaling in lung adenocarcinoma.
1/2016ROR1 sustains caveolae and survival signalling as a scaffold of cavin-1 and caveolin-1.

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Motoshi Suzuki Research Topics

Disease

28Neoplasms (Cancer)
08/2022 - 06/2002
10Lung Neoplasms (Lung Cancer)
07/2021 - 11/2010
10Adenocarcinoma of Lung
03/2021 - 04/2011
7Neoplasm Metastasis (Metastasis)
08/2022 - 01/2012
5Neuroblastoma
08/2022 - 09/2007
5Leukemia
05/2020 - 03/2002
4Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
07/2021 - 10/2014
4Prostatic Neoplasms (Prostate Cancer)
03/2021 - 10/2015
4Genomic Instability
11/2010 - 04/2004
3Breast Neoplasms (Breast Cancer)
01/2021 - 11/2009
3Carcinogenesis
03/2013 - 09/2007
2Hypoxia (Hypoxemia)
01/2022 - 10/2015
2Adenocarcinoma
07/2021 - 10/2014
2Colonic Neoplasms (Colon Cancer)
10/2015 - 09/2009
2Chromosome Aberrations (Chromosome Abnormalities)
08/2012 - 06/2008
1Colorectal Neoplasms (Colorectal Cancer)
01/2022
1Disease Progression
03/2021
1Hypergammaglobulinemia (Hyperimmunoglobulinemia)
01/2021
1Reinfection
01/2021
1Lymphatic Metastasis
10/2020
1BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
01/2020
1Malaria
10/2019
1Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
09/2018
1Philadelphia Chromosome
09/2018

Drug/Important Bio-Agent (IBA)

9Messenger RNA (mRNA)IBA
01/2022 - 09/2009
9Proteins (Proteins, Gene)FDA Link
03/2021 - 12/2003
6EnzymesIBA
05/2020 - 12/2003
5dihydroceramide desaturaseIBA
07/2021 - 01/2016
5SphingolipidsIBA
10/2020 - 01/2016
5Pharmaceutical PreparationsIBA
05/2020 - 01/2004
4Receptor Tyrosine Kinase-like Orphan ReceptorsIBA
03/2021 - 01/2016
4MicroRNAs (MicroRNA)IBA
07/2017 - 11/2008
4Tretinoin (Retinoic Acid)FDA LinkGeneric
06/2012 - 03/2002
3Transcription Factors (Transcription Factor)IBA
07/2021 - 01/2014
3Phosphotransferases (Kinase)IBA
03/2021 - 02/2016
3CeramidesIBA
10/2020 - 11/2009
3Carrier Proteins (Binding Protein)IBA
10/2019 - 01/2012
3Sphingomyelin Phosphodiesterase (Sphingomyelinase)IBA
06/2012 - 03/2002
2Proteasome Endopeptidase Complex (Proteasome)IBA
03/2021 - 04/2011
2AndrogensIBA
03/2021 - 10/2015
2UbiquitinIBA
03/2021 - 10/2015
2Imatinib Mesylate (Gleevec)FDA Link
01/2020 - 09/2018
2CytokinesIBA
01/2019 - 08/2012
2Tyrosine Kinase InhibitorsIBA
09/2018 - 03/2012
2Paclitaxel (Taxol)FDA LinkGeneric
01/2017 - 10/2016
2Liposomes (Liposome)IBA
01/2016 - 02/2012
2Daunorubicin (Cerubidine)FDA LinkGeneric
01/2014 - 11/2009
2DNA (Deoxyribonucleic Acid)IBA
01/2014 - 04/2004
2Myosins (Myosin)IBA
11/2012 - 01/2012
2ActomyosinIBA
11/2012 - 01/2012
2Glial Cell Line-Derived Neurotrophic Factor (GDNF)IBA
11/2011 - 09/2007
2DNA-Directed DNA Polymerase (Polymerases, DNA)IBA
11/2010 - 06/2002
2sphingosine kinaseIBA
09/2007 - 12/2003
1polyphyllin DIBA
08/2022
1BuffersIBA
08/2022
1Phosphates (Orthophosphate)IBA
08/2022
1SolutionsIBA
08/2022
1lysoplasmalogenase (alkenylglycerophosphocholine hydrolase)IBA
01/2022
1phosphatidal ethanolaminesIBA
01/2022
1choline plasmalogensIBA
01/2022
1Phospholipases (Phospholipase)IBA
01/2022
1PlasmalogensIBA
01/2022
1Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA
01/2022
1Complement Factor D (Factor D)IBA
08/2021
1AdipokinesIBA
08/2021
1Trans-Activators (Trans-Acting Factor)IBA
07/2021
1Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
03/2021
1geldanamycinIBA
03/2021
1HSP27 Heat-Shock ProteinsIBA
03/2021
1Racemases and Epimerases (Epimerases and Racemases)IBA
03/2021
1Heat-Shock Proteins (Heat-Shock Protein)IBA
03/2021
1Coenzyme A (CoA)IBA
03/2021
1Docetaxel (Taxotere)FDA Link
03/2021
1Androgen Receptors (Androgen Receptor)IBA
03/2021
1Propidium (Propidium Iodide)IBA
01/2021
1Growth Hormone (Somatotropin)IBA
01/2021
1vaticanol CIBA
05/2020
1Nuclear Proteins (Protein, Nuclear)IBA
01/2020
1ponatinibIBA
01/2020
1venetoclaxIBA
01/2020
1AZD5991IBA
01/2020
1AntigensIBA
10/2019
1VaccinesIBA
10/2019
1Galactosylceramides (Galactocerebrosides)IBA
01/2019
1Taxoids (Taxanes)IBA
01/2017
1cabazitaxelFDA Link
10/2016
1ResveratrolIBA
02/2016
1RV 538 (PDMP)IBA
01/2016
1Dimyristoylphosphatidylcholine (DMPC)IBA
01/2016
1ceramide glucosyltransferaseIBA
01/2016
1Glucose (Dextrose)FDA LinkGeneric
10/2015
1Acid CeramidaseIBA
10/2015
1Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA
10/2015
1Deubiquitinating EnzymesIBA
10/2015
1lysyl- arginyl- alanyl- lysyl- alanyl- lysyl- threonyl- threonyl- lysyl- lysyl- arginine (PKCS)IBA
01/2014
1DNA Ligase ATPIBA
01/2014
1Myosin Light Chains (Myosin Essential Light Chain)IBA
11/2012
1Nonmuscle Myosin Type IIAIBA
11/2012
1rho-Associated KinasesIBA
11/2012
1T-Cell Antigen Receptors (T-Cell Receptor)IBA
08/2012